Precise SDF1-mediated cell guidance is achieved through ligand clearance and microRNA-mediated decay
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چکیده
منابع مشابه
Precise SDF1-mediated cell guidance is achieved through ligand clearance and microRNA-mediated decay
During animal development, SDF1 simultaneously guides various cell types to different targets. As many targets are in close proximity to one another, it is unclear how the system avoids mistargeting. Zebrafish trigeminal sensory neurons express the SDF1 receptor Cxcr4b and encounter multiple SDF1 sources during migration, but ignore all but the correct one. We show that miR-430 and Cxcr7b regul...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2013
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.201207099